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When slimy stud Dr. Chris Leeder (Jack Buddliner) takes possession of Dr. Jekyll's ancient notebook, he quickly becomes obsessed with the murderous sex crimes of the original Mr. Hyde. Ignoring the notebook's warning that the Jekyll & Hyde formula "makes people appear as they really are," the demented doc mixes the potion and promptly turns into..."Mrs. Hyde" (Jane Tsentas), a sexy blonde in a mini skirt who just happens to be a homicidal nymphomanic!
After enjoying a lesbian romp with Leeder's secretary (legendary skin flick starlet Rene Bond), and the sadistic slaughter of a drunken sailor (ouch!), Miss Hyde decides to pay a visit to Leeder's fiancee (Jennifer Brooks) and permanently cancel the wedding. Gender bending adult horror.